Mast ComplX™

Mast ComplX™

  • A white plastic bottle of ALIGHT Mast CompLex dietary supplement with a blue and teal logo on the front label, set against a plain white background.
  • A white bottle of Alight Mast ComplX dietary supplement with text describing its benefits like, mast cell stability, histamine support, calmer allergy response, and more.
  • Text on the right reads 'How To Take Mast ComplX' with dosage instructions, on a light off-white background - 3 capsules a day, best divided throughout the day.
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  • A black-and-white Supplement Facts label showing a list of ingredients and daily value information for a dietary supplement. Visible ingredients include Biotin, Nettle, Catmint, Perilla, Hops, Chinese Skullcap Extract, Mangosteen Extract, American Ginseng, Quercetin, and Luteolin.
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Mast ComplX™

Mast ComplX™

Mast Cell Support*

$67.93 USD
$67.93 USD
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Key Benefits

  • Supports healthy mast cell stability and a balanced inflammatory response*
  • Supports normal histamine levels through multiple complementary pathways*
  • Supports a healthy response to both allergy-triggered and non-allergy-triggered reactions*
  • Supports a less reactive system over time with consistent use*

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Description

Mast ComplX™: Mast Cell Support*


90 vegetarian capsules


Most histamine support products address one piece of a much larger puzzle. They block histamine receptors after the fact, leaving the other 1,000+ inflammatory molecules that mast cells release completely unaddressed. For those dealing with mold-related challenges, mast cell reactivity, or sensitivities that respond to everything, that's not enough.


Mast ComplX™ works upstream rather than simply blocking histamine receptors. This formula stabilizes mast cells before they degranulate, reducing the release of not just histamine, but tryptase, leukotrienes, prostaglandins, and the full cascade of pro-inflammatory mediators that drive symptoms — across both allergy-triggered and non-allergy-triggered reactions making it relevant for those who react to meals, temperature changes, stress, and environmental exposures, not just seasonal allergens.


Diamine oxidase (DAO) enzyme supports the breakdown of histamine that has already been released. And American ginseng addresses the stress response that fires during a mast cell reaction, a dimension most formulas never consider.
Together, this means less histamine circulating and fewer triggers reaching mast cells in the first place. Over time, with less histamine load to react to, your system has more room to stay calm. Built for those who need more than basic histamine blocking.*


*This statement has not been approved by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent a disease.

How to Use

  • Take 3 capsules daily, best divided, or as directed by your health care practitioner.

Ingredients

Ingredients in 3 capsules:

  • Biotin 20mcg
  • Nettle (Urtica dioica) (leaf powder) 500mg
  • Catmint (Nepeta bracteata) (leaf powder) 300mg
  • Perilla (Perilla frutescens) (leaf powder) 250mg
  • Hops (Humulus lupulus) (flower powder) 200mg
  • Chinese Skullcap Extract (Scutellaria baicalensis) (root) (85% baicalin) 100mg
  • Mangosteen Extract (Garcinia mangostana) (fruit) (10% Mangostin) 100mg
  • American Ginseng (Panax quinquefolius) (root powder) 80mg
  • Quercefit® Quercetin Indena Phytosome™ (Sophora japonica L. Extract) (flower) (Sunflower lecithin) 80mg
    Luteolin (from Sophora japonica L. Extract) (whole flower bud) 50mg
  • Diamine Oxidase (from pea sprouts) (Pisum sativum Linn.) (providing 20,000 HDU per serving) 20mg

Quercefit® and Indena Phytosome™ are trademarks owned by Indena S.p.A., Italy.

Other ingredients:
Hypromellose (Vegetable Capsule).

Does Not Contain:
Gluten, soy

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Customer Reviews

Loved by 10,000+ Customers

Why Choose Mast ComplX™

Finally, a Mast Cell Formula That Goes Beyond Histamine

Mast cells release over 1,000 inflammatory molecules when triggered, and most products only address one of them. Mast ComplX™ was built to change that.

  • MCAS & Mold Reactivity

    MCAS & Mold Reactivity

    Mold exposure is a well-recognized trigger for mast cell overactivation. Mast ComplX™ supports stability at the mast cell level, built for those navigating environmentally triggered immune challenges daily.*
  • Beyond Histamine

    Beyond Histamine

    Mast ComplX™ goes beyond histamine to support healthy levels of tryptase, leukotrienes, prostaglandins, and other pro-inflammatory mediators released during mast cell degranulation.*
  • React to Everything?

    React to Everything?

    Whether your reactions are triggered by food, heat, stress, or environmental exposure, Mast ComplX™ supports a healthy mast cell response to both allergy and non-allergy triggers.*
  • Builds Over Time

    Builds Over Time

    This is a long game formula, meaning less histamine circulating and fewer triggers reaching mast cells in the first place. Over time, with less histamine load to react to, your system has more room to stay calm.*
What's Inside

Premium Ingredients, Quality Sourced.

Every capsule is packed with clinically studied, bioavailable nutrients. No fillers, no fluff.

  • Nettle
    500mg

    Urtica dioica

    A foundational herb in mast cell support, nettle leaf works to stabilize mast cells before they degranulate, reducing the release of histamine and a broad spectrum of other pro-inflammatory mediators. Supports a healthy response to both allergy-triggered and environmental triggers.*

  • Catmint
    300mg

    Nepeta bracteata

    A cooling and calming herb with a long history of use for nervous system support. Catmint addresses the neuroinflammatory component of mast cell reactivity, supporting a calmer, less reactive neurological environment during immune challenges.*

  • Perilla
    250mg

    Perilla frutescens

    A well-researched herb known for its role in supporting healthy leukotriene and prostaglandin levels. Perilla helps address the full inflammatory cascade beyond histamine, supporting a balanced immune response to environmental and dietary triggers.*

  • Chinese Skullcap Extract
    100mg

    Scutellaria baicalensis

    One of the most studied flavonoids for mast cell support. Chinese skullcap helps inhibit the release of histamine and other inflammatory mediators, supporting a healthy immune and inflammatory response at the mast cell level.*

  • American Ginseng
    80mg

    Panax quinquefolius

    A dimension most mast cell formulas never consider. American ginseng supports a healthy stress response, addressing the adrenal and nervous system activation that fires during a mast cell reaction and can amplify symptoms.*

  • Quercefit® Quercetin Indena Phytosome™
    80mg

    Sophora japonica L. Extract

    The most bioavailable form of quercetin available, delivered via phytosome technology for superior absorption. Quercetin supports histamine receptor modulation and healthy immune signaling, and works synergistically with the mast cell stabilizing herbs throughout this formula.*

  • Diamine Oxidase
    20mg

    Pisum sativum Linn.

    The primary enzyme responsible for breaking down histamine in the digestive tract and bloodstream. Included at 20,000 HDU per serving, this vegetarian-sourced DAO supports the body's natural histamine clearance for those who need additional enzymatic support.*

  • Nettle
    500mg

    Urtica dioica

    A foundational herb in mast cell support, nettle leaf works to stabilize mast cells before they degranulate, reducing the release of histamine and a broad spectrum of other pro-inflammatory mediators. Supports a healthy response to both allergy-triggered and environmental triggers.*

  • Catmint
    300mg

    Nepeta bracteata

    A cooling and calming herb with a long history of use for nervous system support. Catmint addresses the neuroinflammatory component of mast cell reactivity, supporting a calmer, less reactive neurological environment during immune challenges.*

  • Perilla
    250mg

    Perilla frutescens

    A well-researched herb known for its role in supporting healthy leukotriene and prostaglandin levels. Perilla helps address the full inflammatory cascade beyond histamine, supporting a balanced immune response to environmental and dietary triggers.*

  • Chinese Skullcap Extract
    100mg

    Scutellaria baicalensis

    One of the most studied flavonoids for mast cell support. Chinese skullcap helps inhibit the release of histamine and other inflammatory mediators, supporting a healthy immune and inflammatory response at the mast cell level.*

  • American Ginseng
    80mg

    Panax quinquefolius

    A dimension most mast cell formulas never consider. American ginseng supports a healthy stress response, addressing the adrenal and nervous system activation that fires during a mast cell reaction and can amplify symptoms.*

  • Quercefit® Quercetin Indena Phytosome™
    80mg

    Sophora japonica L. Extract

    The most bioavailable form of quercetin available, delivered via phytosome technology for superior absorption. Quercetin supports histamine receptor modulation and healthy immune signaling, and works synergistically with the mast cell stabilizing herbs throughout this formula.*

  • Diamine Oxidase
    20mg

    Pisum sativum Linn.

    The primary enzyme responsible for breaking down histamine in the digestive tract and bloodstream. Included at 20,000 HDU per serving, this vegetarian-sourced DAO supports the body's natural histamine clearance for those who need additional enzymatic support.*
Our Quality Promise

✓ Respect for bioavailability & purity

✓ No artificial colors, flavors, or sweeteners

✓ Free of common allergens

✓ Research-backed ingredients & formulation

✓ Clinically formulated practitioner grade by design

🔬

Lab Tested

3rd party purity guarantee

🌿

Low Allergen

Capsules, liquids, softgels and more

🎖️

GMP Certified

cGMP facility

🌍

Sustainably Sourced

Non-synthetic

  • 5 stars: 1 (100%)
  • 4 stars: 0 (0%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
J
Judy
Real results

Thank-you for this product- I genuinely feel great results when I was in an environment that I needed to be in for a few weeks-it definitely helped keeping allergies symptoms under control.

Judy review photo

Got Questions?

Frequently Asked Questions

Everything you need to know about Mast ComplX™ to get back to feeling like you.

What is Mast ComplX™ and who is it designed for?

Mast ComplX™ is a comprehensive mast cell and histamine support formula designed for those dealing with mast cell overactivation, histamine sensitivity, or environmentally triggered immune challenges. It is also relevant for those with seasonal allergies or histamine sensitivity who have found basic antihistamine or quercetin products insufficient.*

How does Mast ComplX™ differ from a basic histamine blocker or quercetin supplement?

Most antihistamines and quercetin supplements block histamine receptors after histamine has already been released. Mast ComplX™ works upstream, supporting mast cell stability before degranulation occurs and reducing the release of histamine alongside tryptase, leukotrienes, prostaglandins, and other pro-inflammatory mediators. It also includes DAO enzyme to break down circulating histamine and American ginseng to support the stress response triggered during a mast cell reaction.*

What is tryptase and why does it matter?

Tryptase is an enzyme mast cells produce to digest their own cell wall, allowing them to break open and release their inflammatory contents. Supporting healthy tryptase levels is a key part of stabilizing the mast cell response upstream, rather than managing symptoms after degranulation has already occurred.*

How do I take Mast ComplX™ and how long does one bottle last?

The recommended dose is 3 capsules daily with or without meals, or as directed by your healthcare practitioner. Each bottle contains 90 capsules, providing a 30-day supply at the standard dose.

Is Mast ComplX™ appropriate for children?

Mast ComplX™ may be appropriate for children following Clark's Rule dosing adjustments. We recommend consulting your healthcare practitioner before giving any new supplement to a child, particularly those navigating environmentally triggered immune challenges.

Can I open the capsules and mix with food or liquid?

Yes, the capsules can be opened and mixed into food or liquid. Keep in mind some of the herbal ingredients have a bitter, earthy taste so mixing with a strongly flavored liquid or food works best.

Is Mast ComplX™ third-party tested?

Yes. Every batch undergoes rigorous third-party laboratory testing for heavy metals, microbial contaminants, and potency verification. Our manufacturing facility follows strict current Good Manufacturing Practice (cGMP) guidelines enforced by the FDA.

Is it vegan / gluten-free / soy-free / dairy-free?

Yes. Mast ComplX™ is vegan, and every batch is tested free of gluten and soy. The ingredients themselves are dairy-free, however Mast ComplX™ is manufactured in a facility that also processes dairy, so we cannot guarantee it is free of dairy cross-contact. If you have a severe dairy allergy or sensitivity, please consult your healthcare provider before use.

Still have questions?

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