PROTOCOLS

Aflatoxin

ASPERGILLUS FLAVUS, A. PARASITICUS

Aflatoxins as a class are acutely toxic. They primarily impact the liver, however the detoxification burden is also shared with the kidneys.

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Gliotoxin

ASPERGILLUS SPP., TRICHODERMA SPP.

Gliotoxin opens the doorway to fungal infection. It can be produced in vivo, contributing to the etiology of fungal infections, and is a virulence factor for the airborne pathogen Aspergillus fumigatus.

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Mycophenolic Acid

PENICILLIUM SPP., ASPERGILLUS SPP., EUROTIUM REPENS

Mycophenolic acid (MPA) is a mold metabolite that’s excreted from mold as it’s digesting and metabolizing the substrate it’s growing upon.

Increased MPA is highly suggestive of current exposure to mold, because where there’s living mold, there’s MPA, but not necessarily mycotoxins.

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Ochratoxin

ASPERGILLUS OCHRASEUS, A. NIGER, PENICILLIUMVERRUCOSUM, P. NORDICUM, P. CHRYSOGENUM

Ochratoxin is a persister mycotoxin. It binds tightly to the blood protein albumin, acting like a mobile reserve, resulting in an extended time in the blood. The kidneys are the primary route of excretion, which sustain significant damage in the process.

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Mold & Mycotoxins

Mycotoxins are secondary metabolites that are released from mold as a competitive
advantage over other microbes in a hospitable environment, which is related to spaces with
higher levels of humidity. Many mold species that also enjoy an environment as humans do
are mycotoxin formers.

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Citrinin

Temporary grain-free diet to avoid possible Citrinin contamination.

Focus on: Butyrate-rich foods (butter, cabbage, radicchio, white part of spring onion, broccoli, Brussels sprouts).
Radishes, as a source of pelargonidin (which has a Citrinin-specific liver protective effect).

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Chaetoglobosin

Proline and tyrosine-rich animal and fish protein (muscle, glands, and skin), organic dairy, cruciferous vegetables (sulforaphane as Nrf2 activator to enhance cellular resilience). May benefit from avoidance of alkaloid-containing foods (i.e. coffee, cacao, tea, tomatoes, and potatoes).

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Trichothecenes

Green tea with lemongrass. High oleic and linoleic oils (olive, avocado, grape seed, sunflower.) Brassicaceae family (bok choy, broccoli, Brussels sprouts, cabbage, cauliflower, collard, kale, kohlrabi, rutabaga, turnip.)

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